Papers & Publications
Znomics scientists and scientific advisors participated in research and/or authoring of the following papers and publications:
Insertional Mutagenesis in Zebrafish Rapidly Identifies Genes Essential for Early Vertebrate Development
In the academic world, retroviral insertional mutagenesis has been used to identify genes required for normal vertebrate development. Greg Golling and Wenbiao Chen then joined Znomics to create the proprietary tools to make this technology useful on a commercial scale. [Download PDF]
By Gregory Golling, Adam Amsterdam, Zhaoxia Sun, Marcelo Antonelli, Ernesto Maldonado, Wenbiao Chen, Shawn Burgess, Maryann Haldi, Karen Artzt, Sarah Farrington, Shuh-Yow Lin, Robert M. Nissen, Nancy Hopkins
Published by Nature Publishing Group http://genetics.nature.com, 13 May 2002, DOI: 10.1038/ng896
In Vivo Drug Discovery in the Zebrafish
In this paper, Znomics Scientific Advisory Board member Dr. Len Zon reviews the reasons why the zebrafish is becoming a new model for drug discovery. [Download PDF]
By Leonard I. Zon and Randall T. Peterson
Published in Nature Reviews, Drug Discovery, Volume 4, January 2005
Agouti-Related Protein (AGRP) Is Conserved and Regulated by Metabolic State in the Zebrafish, Danio rerio
Dr. Cone's laboratory at OHSU and Znomics scientists have collaborated to determine that the brain circuitry regulating body weight in humans is conserved in the zebrafish. [Download PDF]
By Youngsup Song, Gregory Golling, Theresa L. Thacker, and Roger D. Cone
Published in Endocrine, vol. 22, no. 3, 257–265, December 2003 0969–711X/03/22:257–265
Creation of a Genetic Model of Obesity in a Teleost
This manuscript, from Dr. Cone's laboratory at OHSU describes the creation of the first genetic model of obesity in the fish. [Download PDF]
By Youngsup Song and Roger D. Cone
Published in The FASEB Journal article fj.06-7503com, March 6, 2007
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